The Difference between Amphetamines and Cathinones

Cathinones are, strictly speaking, a subset of amphetamines - however, the subtle differences between them warrant this sub-family to be treated as a class of its own.

There is a surprising phenomenon, when it comes to molecules - that small changes to molecules sometimes create very profound changes in effect, This tendency to reliably contradict our intuition - is called the QSAR Paradox. This paradox is part of a larger problem found in the determination of molecular similarity in chemistry.

Richard Glennon studied the QSAR between cathinones and amphetamines and published his findings.

Willett_1998

.pdf

Download PDF • 150KB

glennon2016

.pdf

Download PDF • 1.11MB