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The Difference between Amphetamines and Cathinones


Cathinones are, strictly speaking, a subset of amphetamines - however, the subtle differences between them warrant this sub-family to be treated as a class of its own.

There is a surprising phenomenon, when it comes to molecules - that small changes to molecules sometimes create very profound changes in effect, This tendency to reliably contradict our intuition - is called the QSAR Paradox. This paradox is part of a larger problem found in the determination of molecular similarity in chemistry.

Richard Glennon studied the QSAR between cathinones and amphetamines and published his findings.






















Willett_1998
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glennon2016
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