In 1860, a German scientist named Albert Niemann extracted and isolated the active ingredient in coca leaves for the first time and gave...

The first is an experience that Alexander Shulgin documented and devoted an entire chapter to in PiHKaL, the second is actually an experience from my own personal life. Chapter 13 in PiHKaL is called "Time Stop"

This testimony of Xenophon, from more than 2,500 years ago, is the earliest documentation of a unique phenomenon known as 'mad honey'.

The good people of NIDA made generous development budgets available to researchers who would develop synthetic versions of natural cannabinoids such as THC or CBD. The most diligent and prolific researcher who used NIDA money to this end was an American professor of organic chemistry named John William Huffman, who developed over 400 such analogs.